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1

Is it possible to achieve bio-equivalence between an oral solid immediate-release and an analogue enteric-coated formulation?

Licht, Dannit, Cohen, Rachel, Spiegelstein, Ofer, Rabinovich-Guilatt, Laura, Zholkovsky, Marina, Gilbert, Adrian, Dressman, Jennifer B., Safadi, Muhammad

Journal:

Journal of Pharmacy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 425 KB

english, 2016

2

CHEMICAL TREATMENTS TO IMPROVE THE QUALITY OF CUT GYPSOPHILA FLOWERS

Tandler, J., Mor, Y., Spiegelstein, H., Mayak, S.

Journal:

Acta Horticulturae

Year:

1986

File:

PDF, 228 KB

1986

3

Enantioselective synthesis and teratogenicity of propylisopropyl acetamide, a CNS-active chiral amide analogue of valproic acid

Ofer Spiegelstein, Meir Bialer, Matthias Radatz, Heinz Nau, Boris Yagen

Journal:

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

4

Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice

Ofer Spiegelstein, Michelle Y. Merriweather, Ned J. Wicker, Richard H. Finnell

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2003

Language:

english

File:

PDF, 87 KB

english, 2003

5

Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation

Ofer Spiegelstein, Laura E. Mitchell, Michelle Y. Merriweather, Ned J. Wicker, Qiang Zhang, Edward J. Lammer, Richard H. Finnell

Journal:

Developmental Dynamics

Year:

2004

Language:

english

File:

PDF, 1.51 MB

english, 2004

6

Early changes in the membrane of HeLa cells adsorbing sendai virus under conditions of fusion

P. Fuchs, M. Spiegelstein, M. Haimsohn, J. Gitelman, A. Kohn

Journal:

Journal of Cellular Physiology

Year:

1978

Language:

english

File:

PDF, 912 KB

english, 1978

7

Teratogenicity of valproate conjugates with anticonvulsant activity in mice

Ofer Spiegelstein, Nithiananda Chatterjie, George Alexander, Richard H Finnell

Journal:

Epilepsy Research

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

8

Isolation of N,N-dialkylated derivatives of valproylglycinamide from dog plasma by active charcoal adsorption and their quantification by high-performance liquid chromatography

Ofer Spiegelstein, Meir Bialer, Boris Yagen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 336 KB

english, 1997

9

Absolute configuration of the four stereoisomers of valnoctamide (2-ethyl-3-methyl valeramide), a potentially new stereospecific antiepileptic and CNS drug

Michael Roeder, Ofer Spiegelstein, Volker Schurig, Meir Bialer, Boris Yagen

Journal:

Tetrahedron: Asymmetry

Year:

1999

Language:

english

File:

PDF, 290 KB

english, 1999

10

Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma

Nina Isoherranen, Boris Yagen, Ofer Spiegelstein, Amir Steinman, Richard H Finnell, Meir Bialer

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 647 KB

english, 2003

11

Developmental Outcome of Levetiracetam, Its Major Metabolite in Humans, 2-Pyrrolidinone N-Butyric Acid, and Its Enantiomer (R)-α-ethyl-oxo-pyrrolidine Acetamide in a Mouse Model of Teratogenicity

Nina Isoherranen, Ofer Spiegelstein, Meir Bialer, Jing Zhang, Michelle Merriweather, Boris Yagen, Michael Roeder, Aleata A. Triplett, Volker Schurig, Richard H. Finnell

Journal:

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

12

Pathobiology and Genetics of Neural Tube Defects

Richard H. Finnell, Amy Gould, Ofer Spiegelstein

Journal:

Year:

2003

Language:

english

File:

PDF, 107 KB

english, 2003

13

Cytokinins in cut carnation flowers. II. Relationship between endogenous ethylene and cytokinin levels in the petals

J. Staden, B. C. Featonby-Smith, S. Mayak, H. Spiegelstein, A. H. Halevy

Journal:

Plant Growth Regulation

Year:

1987

Language:

english

File:

PDF, 734 KB

english, 1987

14

Effect of temperature on ethylene biosynthesis in carnation petals

A. Borochov, H. Itzhaki, H. Spiegelstein

Journal:

Plant Growth Regulation

Year:

1985

Language:

english

File:

PDF, 455 KB

english, 1985

15

Translocation of 14C-assimilates in roses : II. The effect of shoot darkening and cytokinin application

Yoram Mor, Hanna Spiegelstein, Abraham H. Halevy

Journal:

Physiologia Plantarum

Year:

1981

Language:

english

File:

PDF, 401 KB

english, 1981

16

The site of 1-aminocyclopropane-1-carboxylic acid synthesis in senescing carnation petals

Yoram Mor, Abraham H. Halevy, Hanna Spiegelstein, Shimon Mayak

Journal:

Physiologia Plantarum

Year:

1985

Language:

english

File:

PDF, 823 KB

english, 1985

17

A rhythm in the flowering response of photoperiodically-induced Pharbitis nil to agents affecting cytosolic calcium and pH

Haya Friedman, Eliezer E. Goldschmidt, Hanna Spiegelstein, Abraham H. Halevy

Journal:

Physiologia Plantarum

Year:

1992

Language:

english

File:

PDF, 362 KB

english, 1992

18

Involvement of signal transduction pathway components in photoperiodic flower induction in Pharbitis nil

Amihud Borochov, Hanna Spiegelstein, Abraham H. Halevy

Journal:

Physiologia Plantarum

Year:

1995

Language:

english

File:

PDF, 440 KB

english, 1995

19

Short-chain saturated fatty acids in the regulation of pollination-induced ethylene sensitivity of Phalaenopsis flowers

Abraham H. Halevy, Ron Porat, Hanna Spiegelstein, Amihud Borochov, Louise Botha, Charles S. Whitehead

Journal:

Physiologia Plantarum

Year:

1996

Language:

english

File:

PDF, 5.39 MB

english, 1996

20

Structure-Pharmacokinetic-Pharmacodynamic Relationships of yV-Alkyl Derivatives of the New Antiepileptic Drug Valproyl Glycinamide

Ofer Spiegelstein, Boris Yagen, Meir Bialer

Journal:

Year:

1999

Language:

english

File:

PDF, 734 KB

english, 1999

21

Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents

Nina Isoherranen, Boris Yagen, José H Woodhead, Ofer Spiegelstein, Simcha Blotnik, Karen S Wilcox, Richard H Finnell, Gregory D Bennett, H Steve White, Meir Bialer

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

22

Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice

Nina Isoherranen, Boris Yagen, Ofer Spiegelstein, Richard H Finnell, Michelle Merriweather, Jose H Woodhead, Bogdan Wlodarczyk, H Steve White, Meir Bialer

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

23

Ethylene and flower petal senescence: Interrelationship with membrane lipid catabolism

Amihud Borochoy, Hanna Spiegelstein, Sonia Philosoph-Hadas

Journal:

Physiologia Plantarum

Year:

1997

Language:

english

File:

PDF, 6.67 MB

english, 1997

24

Structure Activity Relationship of Human Microsomal Epoxide Hydrolase Inhibition by Amide and Acid Analogues of Valproic Acid

Ofer Spiegelstein, Deanna L. Kroetz, René H. Levy, Boris Yagen, Sussan I. Hurst, Micha Levi, Abdulla Haj-Yehia, Meir Bialer

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

25

Stereoselective Pharmacokinetics and Pharmacodynamics of Propylisopropyl Acetamide, a CNS-Active Chiral Amide Analog of Valproic Acid

Ofer Spiegelstein, Boris Yagen, René H. Levy, Richard H. Finnell, Gregory D. Bennett, Michael Roeder, Volker Schurig, Meir Bialer

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.26 MB

1999

26

Folate-Regulated Changes in Gene Expression in the Anterior Neural Tube of Folate Binding Protein-1 (Folbp1)-Deficient Murine Embryos

Ofer Spiegelstein, Robert M. Cabrera, Daniel Bozinov, Bogdan Wlodarczyk, Richard H. Finnell

Journal:

Neurochemical Research

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

27

Arsenic-Induced Congenital Malformations in Genetically Susceptible Folate Binding Protein-2 Knockout Mice

Bogdan Wlodarczyk, Ofer Spiegelstein, Janée Gelineau-van Waes, Roseann L. Vorce, Xiufen Lu, Chris X. Le, Richard H. Finnell

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 137 KB

english, 2001

28

Effect of carbobenzoxy derivatives of amino acids on glutamine synthesis and γ-glutamyl transfer

H. Spiegelstein-Klarfeld, N. Lustig, N. Lichtenstein

Journal:

Cellular and Molecular Life Sciences

Year:

1970

Language:

english

File:

PDF, 200 KB

english, 1970

29

Effect of carbobenzoxy, phenylacetyl and phenylpropionyl derivatives of amino acids on mammalian and bacterial asparaginase

H. Spiegelstein-Klarfeld, N. Lustig, N. Lichtenstein

Journal:

Cellular and Molecular Life Sciences

Year:

1974

Language:

english

File:

PDF, 227 KB

english, 1974

30

The impact of hyperlactatemia on postoperative outcome after adult cardiac surgery

Alexander Kogan, Sergey Preisman, Alex Bar, Leonid Sternik, Jacob Lavee, Ateret Malachy, Dan Spiegelstein, Haim Berkenstadt, Ehud Raanani

Journal:

Journal of Anesthesia

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

31

Midterm Results of Mitral Valve Repair: Closed Versus Open Annuloplasty Ring

Dan Spiegelstein, Yaron Moshkovitz, Leonid Sternik, Micha S. Fienberg, Alexander Kogan, Ateret Malachy, Ehud Raanani

Journal:

The Annals of Thoracic Surgery

Year:

2010

Language:

english

File:

PDF, 570 KB

english, 2010

32

Quality of mitral valve repair: Median sternotomy versus port-access approach

Ehud Raanani, Dan Spiegelstein, Leonid Sternik, Sergey Preisman, Yaron Moshkovitz, Aram K. Smolinsky, Amihai Shinfeld

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2010

Language:

english

File:

PDF, 154 KB

english, 2010

33

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies

Ofer Spiegelstein, Amy Gould, Bogdan Wlodarczyk, Marlene Tsie, Xiufen Lu, Chris Le, Aron Troen, Jacob Selhub, Jorge A. Piedrahita, J. Michael Salbaum, Claudia Kappen, Stepan Melnyk, Jill James, Richar

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 198 KB

english, 2005

34

Heparin-free Management of Intra-aortic Balloon Pump after Cardiac Surgery

Alexander Kogan, Sergey Preisman, Leonid Sternik, Boris Orlov, Dan Spiegelstein, Hanoch Hod, Ateret Malachy, Shany Levin, Ehud Raanani

Journal:

Journal of Cardiac Surgery

Year:

2012

Language:

english

File:

PDF, 446 KB

english, 2012

35

Identification and Characterization of the Human and Mouse SLC19A3 Gene: A Novel Member of the Reduced Folate Family of Micronutrient Transporter Genes

James D. Eudy, Ofer Spiegelstein, Robert C. Barber, Bogdan J. Wlodarczyk, Jeffrey Talbot, Richard H. Finnell

Journal:

Molecular Genetics and Metabolism

Year:

2000

Language:

english

File:

PDF, 277 KB

english, 2000

36

Enhanced Angiogenesis With Multimodal Cell-Based Gene Therapy

Terrence M. Yau, Christopher Kim, Guangming Li, Yaoguang Zhang, Shafie Fazel, Dan Spiegelstein, Richard D. Weisel, Ren-Ke Li

Journal:

The Annals of Thoracic Surgery

Year:

2007

Language:

english

File:

PDF, 1.45 MB

english, 2007

37

Invited Commentary

Dan Spiegelstein, Christopher Kim, Terrence M. Yau

Journal:

The Annals of Thoracic Surgery

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

38

Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice

Ofer Spiegelstein, Xiufen Lu, X. Chris Le, Aron Troen, Jacob Selhub, Stepan Melnyk, S. Jill James, Richard H. Finnell

Journal:

Environmental Toxicology and Pharmacology

Year:

2005

Language:

english

File:

PDF, 153 KB

english, 2005

39

Identification of two putative novel folate receptor genes in humans and mouse

Ofer Spiegelstein, James D Eudy, Richard H Finnell

Journal:

Year:

2000

Language:

english

File:

PDF, 362 KB

english, 2000

40

EFFECTS OF Gymnodinium breve TOXIN ON THE SMOOTH MUSCLE PREPARATION OF GUINEA-PIG ILEUM

Y. GRUNFELD, M.Y. SPIEGELSTEIN

Journal:

British Journal of Pharmacology

Year:

1974

Language:

english

File:

PDF, 735 KB

english, 1974

41

EFFECTS OF Gymnodinium breve TOXIN ON THE SMOOTH MUSCLE PREPARATION OF GUINEA-PIG ILEUM

Y. GRUNFELD, M.Y. SPIEGELSTEIN

Journal:

British Journal of Pharmacology

Year:

1974

Language:

english

File:

PDF, 730 KB

english, 1974

42

A quaternary anti-cholinesterase probe for determining the integrity of the blood - brain barrier

Yacov Ashani, Drora Levy, Eli Heyman, Yona Grunfeld, Tamar Kadar, Michael Spiegelstein

Journal:

Year:

1985

Language:

english

File:

PDF, 273 KB

english, 1985

43

Myelinization in long-term cultures of dissociated mammalian neurons

Abraham Shahar, Yona Grunfeld, Michael Y. Spiegelstein, Rachel Monzain

Journal:

Year:

1975

Language:

english

File:

PDF, 4.36 MB

english, 1975

44

Purification and biological activity of Gymnodinium breve toxins

M.Y. Spiegelstein, Z. Paster, B.C. Abbott

Journal:

Year:

1973

Language:

english

File:

PDF, 566 KB

english, 1973

45

Deformation Dynamics and Mechanical Properties of the Aortic Annulus by 4-Dimensional Computed Tomography: Insights Into the Functional Anatomy of the Aortic Valve Complex and Implications for Transcatheter Aortic Valve Therapy

Ashraf Hamdan, Victor Guetta, Eli Konen, Orly Goitein, Amit Segev, Ehud Raanani, Dan Spiegelstein, Ilan Hay, Elio Di Segni, Michael Eldar, Ehud Schwammenthal

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 1.62 MB

english, 2012

46

Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate

Wlodarczyk, Bogdan, Spiegelstein, Ofer, Hill, Denise, Le, X. Chris, Finnell, Richard H.

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 267 KB

english, 2012

47

Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice

Ofer Spiegelstein, Xiufen Lu, X.Chris Le, Aron Troen, Jacob Selhub, Stepan Melnyk, S.Jill James, Richard H. Finnell

Journal:

Toxicology Letters

Year:

2003

Language:

english

File:

PDF, 99 KB

english, 2003

48

Mitral Valve Repair: Isolated Posterior Compared to Anterior or Bileaflet Pathology

Spiegelstein, Dan, Sternik, Leonid, Orlov, Boris, Shinfeld, Amihai, Feinberg, Micha S., Malachy, Ateret, Raanani, Ehud

Journal:

Journal of Cardiac Surgery

Year:

2013

Language:

english

File:

PDF, 120 KB

english, 2013

49

Components of Axillary Bud Inhibition in Rose Plants. IV. Inhibitory Activity of Plant Extracts

Naftaly Zieslin, Hana Spiegelstein and Abraham H. Halevy

Journal:

Botanical Gazette

Year:

1978

Language:

english

File:

PDF, 890 KB

english, 1978

50

Erratum to: Folate-Regulated Changes in Gene Expression in the Anterior Neural Tube of Folate Binding Protein-1 (Folbp1)-Deficient Murine Embryos

Spiegelstein, Ofer, Cabrera, Robert M., Bozinov, Daniel, Wlodarczyk, Bogdan, Finnell, Richard H.

Journal:

Neurochemical Research

Year:

2014

Language:

english

File:

PDF, 130 KB

english, 2014

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